NFL Picks Against The Spread, Week 3: Eli Manning And A Depleted Giants Team Face Cam Newton

Sep 16, 2012; Charlotte, NC, USA; Carolina Panthers quarterback Cam Newton (1) looks to pass in the first quarter. The Panthers defeated the Saints 35-27 at Bank of America Stadium . Mandatory Credit: Bob Donnan-US PRESSWIRE

It is time for our football on Thursday night. You want stars? The NFL has stars for you. Eli Manning, fresh off of a 500+ yard passing performance, leads his beat up offense into Carolina to play Cam Newton and the Panthers. Both teams sit at 1-1 and hope to get on the winning side of things and pick up their second straight win. New York came away with a win over the Tampa Bay Buccaneers, who beat the Panthers in Week 1.

The Panthers are favored by three, a standard home team line. Which team will be the winner, according to the spread?

New York Giants at Carolina Panthers (-3): Eli Manning overcame three interceptions and threw for over 500 yards against the Buccaneers, who actually beat the Panthers in Week 1. However, in this Thursday Night Football contest, Manning will be without three weapons -- running back Ahmad Bradshaw and receivers Hakeem Nicks and Domenik Hixon. Carolina has Cam Newton. What is a gambler to do? As we have seen over the past couple of years, it is hard to count out Newton. Go with the guy that keeps defying odds. Pick: Panthers, -3.

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