Start: QB Michael Vick, Philadelphia Eagles
Week One gave birth to arguably the leagues most explosive offensive unit in Philadelphia, with Michael Vick leading the charge. The Eagles take on a suspect Chargers defensive unit for are not good in the secondary, and I expect Vick to torch them. Chip Kelly eased off the gas against the Redskins on Monday night, this will not happen again. They plan on running close to 100 offensive plays against the Chargers, giving Vick many opportunities to score points, both as a runner and a passer, so expect big games from LeSean McCoy and DeSean Jackson, the Chargers are not a good football team.
Sit: QB Josh Freeman, Tampa Bay Buccaneers
On paper, it may look like a great match-up based on last seasons statistics, but this New Orleans Saints defensive unit managed to hold Matt Ryan an the explosive Atlanta Falcons offense to only 17 points in Week One, they are much improved on last year. Couple that with an uncertain Josh Freeman, who doesn't have the full backing of the organisation, and a banged up offensive line with inconsistent receivers, I don't like the match-up.
Start: RB Darren McFadden, Oakland Raiders
McFadden managed to find the endzone last week against the Indianapolis Colts, something he hasn't done on a regular basis, and appears to be in good shape this year. An injury-free Darren McFadden is a darn good football player. As explosive as any back in the league and the size to move the pile, and he will get the goal-line carries. He is their best offensive weapon. The Jacksonville Jaguars to not have a great defense, and are weak against the run. Both Terrelle Pryor and Darren McFadden should have great days rushing.
Sit: RB Rashard Mendenhall, Arizona Cardinals
With with running backs such as Shane Vereen, Vick Ballard and Le'Veon Bell out for the foreseeable future, many fantasy players will be considering Mendenhall as an RB2 or flex play this week. Don't. Mendenhall averaged 3.75 YPC last week, with 60 yards total rushing, he had an average game and I expect the same. The Cardinals' offensive line is average at best, especially without Jonathan Cooper, and the Detroit Lions defensive line is a formidable bunch, I don't expect a good day for the Cardinals run-game.
Start: WR Michael Floyd, Arizona Cardinals
The Cardinals cannot rely upon the run-game for a successful offense this week, but they sure as hell can rely on the passing game. The Cardinals had three receivers last week get close to 100 yards, and with Fitzgerald now down as a game-time-decision, who knows whether he'll play, let alone his role in the offense. I expect Michael Floyd to have a big day against a porous Lions secondary. Floyd is a great flex play this week.
Sit: WR Greg Jennings, Minnesota Vikings
Even though he is the only viable Viking play in fantasy football other than Adrian Peterson, this is not a great match-up for Greg Jennings this week. The Chicago Bears are tough against the pass, and quarterback Christian Ponder is still experiencing growing pains in the NFL. I don't think he is the long-term answer in Minnesota, he is inconsistent as a passer and will likely throw a number of picks against a Bears defense which creates turnovers for fun. Not to mention that Jennings has only recorded more than 60 yards receiving once against the Bears in his career. Avoid all Vikings, expect the bionic-man Peterson.
Start: TE Jordan Cameron, Cleveland Browns
Cameron proved his worth to Brandon Weeden and the Browns in Week One with a great game. He is their only reliable target on offense with Josh Gordon still suspended. They face off against the Baltimore Ravens, which is a pretty nice match-up. The Ravens failed to stop a relative unknown in Julius Thomas last week in their loss to the Broncos. Cameron won't have as big of a day, but he'll put up another great fantasy start at the position.
Sit: TE Jermaine Gresham, Cincinnati Bengals
All of a sudden, there are a lot of mouths to feed in the Bengals offense. AJ Green is, well, AJ Green, there's Mohamed Sanu, Gresham, rookie running back Giovani Bernard out of the backfield, and not to mention first round pick Tyler Eifert. Eifert will slowly eat into Gresham's targets going forward, making neither great starts in a standard 10-team league. There are too many other viable options at the position now to be starting Jermaine Gresham.