Here are some facts about the game.
Arizona has not played any other team more than the Giants. This game is the 125th game between the two teams, dating back to 1926. New York has dominated the matchup. The Cardinals' record against the Giants is 42-80-2.On the road, they are 20-48.
The last time the two teams met, it was a 31-27 win for the Giants, and it was not without controversy, as there was a fumble by Victor Cruz that was ruled not a fumble, as it was decided he had "given himself up" on the play to end it. Beanie Wells had one of his finest games in his career that game, rushing for 138 yards and three scores.
Arizona last beat New York in 2009.
After one week of play, Arizona is 20th in the league in scoring points. The Giants, who scored only 14 against the Chargers, are 27th. In terms of offensive yardage, Arizona piled up over 400 in Week 1, good for 10th overall, while the Giants are second to last with 197.
Defensively, Arizona allowed 290 total yards in Week 1, good for sixth in the league. New York is 26th.
Arizona held San Diego to 52 rushing yards. New York mustered only 53 against the Lions. Arizona rushed for 109 in Week 1.
Arizona's Antonio Cromartie has 10 career interceptions at MetLife Stadium. That is tied with Corey Webster for the most at that stadium.
Arizona has no former Giants players, but the Giants have some former Cardinals.
Safety Antrel Rolle was a Cardinals first round pick in 2005. He played through 2009 before signing with the Giants. Dominique Rodgers-Cromartie was also a Cardinals first rounder, drafted in 2008. He played through 2010 in Arizona before being traded in the Eagles as part of the deal to bring Kevin Kolb to Arizona. DRC signed this past offseason with the Giants.
Cornerback Trumaine McBride was with Arizona in 2010. He led the team with 15 special teams tackles that year.
Another player, receiver Corey Washington, was with the Cardinals for about 10 days in the offseason. He was an undrafted rookie signed by the Cardinals in May. He was also released in May.
There are family connections. Arizona tight end Darren Fells and New York tight end Daniel Fells are brothers. Arizona's Antonio Cromartie and New York's Dominique Rodgers-Cromartie are cousins.
If Carson Palmer throws for at least 300 yards against the Giants, he will become only the second QB in team history to throw for 300 yards or more in each of the first two games of a season. The only other to do so was Charley Johnson in the 60s.
With 100 yards receiving, Michael Floyd would become the first Cardinals receiver since David Boston in 2000 to break the 100-yard mark in each of the first two games of the year.
Larry Fitzgerald can tie Hall of Famer Don Maynard for 11th all time with a touchdown catch. It would give him 88 in his career.
With a sack, Calais Campbell will move up to eighth in team history with 37.5 career sacks.