Wow. Sunday saw nine underdogs win against the spread. I personally got killed, going 2-11 on Sunday. So if you don't want my advice anymore, I would understand. I'll try to make it up over the course of the season.
Giants at Lions (-5.5): I want to say that the home team has the edge. And I like the Detroit offense, especially against the New York defense. Plus, you have that Detroit defensive line facing New York's offensive line. That should give them the edge they need. I'll give up the 5.5 points and take the home team.
Chargers at Cardinals (-3): Arizona is only given the standard home team advantage, which tells you the two teams are pretty seven. I think both teams present a challenge to the other. Arizona has some injury doubt. Will Andre Ellington or Tyrann Mathieu play? Even if not, the offensive upgrades should be enough to move the ball down the field against a porous San Diego defense. Carson Palmer has a lifetime 116+ QB rating against the Chargers and has thrown 14 TDs and only three interceptions in six games. Arizona's defense will shut down the San Diego running game. It will be a shootout, but I take the home team, giving up the three points.