Arizona Cardinals Open Season as Huge Favorites against New England Patriots

The Arizona Cardinals are in an unfamiliar position to open the 2016 NFL season. Not only are they a opening up in primetime on Sunday Night Football against the New England Patriots, but they are Super Bowl favorites.

Then you look at the matchup against the Patriots on Sunday Night Football and they are not just favorites, but they are big time favorites going up against the Tom Brady-less Patriots squad.

If you take a look at the lines on OddsShark, the Cardinals have one of the biggest lines in the NFL in week one.

It is not a surprise with the Patriots being out several key players including Tom Brady. What is a surprise is how much the line has moved since it the schedule release, when the Patriots began as a slight favorite at -1.

Now, the Arizona Cardinals sit as a -6 favorite.

While being down several key factors is big, Bill Belichick has had five months of preparation for this game and if it was my money, it is always tough to bet that big against a Belichick coached team.

What do you think? Is a touchdown win something the Arizona Cardinals can expect in week one? Would you bet on the line?