The Arizona Cardinals will look a big different on offense when they start game two of the regular season.
Four starters from game one:
David Johnson
D.J. Humphries
Mike Iupati
John Brown
Will not play on Sunday against the Colts.
Iupati, Smokey Brown and Humphries are all ruled out for Sunday.
— Darren Urban (@Cardschatter) September 15, 2017
In their place comes Kerwynn Williams, John Wetzel, newly acquired Alex Boone and Jaron Brown.
In addition to the new starters, young players Elijhaa Penny and Chad Williams are likely to get work on Sunday.
Maybe the best news to come out of Bruce Arians press conference is that Robert Nkemdiche will make his season debut against the Indianapolis Colts.
Also, there is a chance that $LB Deone Bucannon will get on the field as well.
DL Nkemdiche will make season debut against Indy and will be full go. LB Bucannon a game-time decision. Will have limited role if he plays.
— Kyle Odegard (@Kyle_Odegard) September 15, 2017
It has been a rough beginning to the season for the Cardinals, even before the cavalcade of injuries beset the team, now going into week two, with maybe their season on the line, only 8% of teams make the playoffs after starting 0-2, they'll be without four expected starters.
It'll be Carson Palmer and Bruce Arians rising to the occasion and formulating a plan to get the offense going despite all the injuries.