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Monday Night Football 2022: Los Angeles Rams at San Francisco 49ers odds, picks and more

There’s a huge NFC West showdown in the Bay Area tonight.

2022 NFL Draft - Rounds 2-3 Photo by Kevin Sabitus/Getty Images

There is a legitimate chance there is a four-way tie for first place in the NFC West after tonight’s Monday Night Football matchup.

That is what we are hoping for as Arizona Cardinals fans, because reinforcements are on the way, while other teams are dealing with big injuries and losses.

If the Cardinals can continue to tread water and stay healthy, they give themselves a great chance to finish the season strong.

Let’s see what happens on Monday Night Football, here is everything you need to know.

  • Game: San Francisco 49ers (1-2) vs Los Angeles Rams (2-1)
  • Start Time: 5:15 pm Arizona time on October 3rd, 2022
  • Location: Levi’s Stadium - Santa Clara, CA
  • TV Channel: ESPN
  • Announcers: Joe Buck (play-by-play), Troy Aikman (analyst), Lisa Salters (sideline)
  • Streaming: ESPN+
  • Alternative TV: ESPN2 will once again provide the ManningCast with Peyton and Eli Manning discussing the game
  • Odds: 49ers -1.5 per our friends at Draftkings Sportsbook
  • Over/Under: 42.5