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Cardinals vs. 49ers: How to watch, game time, TV schedule, streaming and more

NFL: Arizona Cardinals at San Francisco 49ers Cary Edmondson-USA TODAY Sports

It is Monday Night Football.

How will the Arizona Cardinals do tonight on National TV? This is their second game of the season on National TV, so let’s hope they play as well tonight as they did against the Saints.

Here is everything you need to know about Monday Night Football in Mexico City.

  • Game: San Francisco 49ers (5-4) at Arizona Cardinals (4-6)
  • Start Time: 6:15 pm Arizona time on November 21, 2022
  • Location: Estadio Azteca - Mexico City, Mexico
  • TV Channel: ESPN
  • Announcers: Joe Buck (play-by-play), Troy Aikman (analyst), Lisa Salters (sideline)
  • Streaming: ESPN+
  • Alternative TV: ESPN2 will once again provide the ManningCast with Peyton and Eli Manning discussing the game
  • National Radio: Westwood One | Ryan Radtke (play-by-play) and Mike Golic (analyst)
  • Odds: Cardinals +8 per our friends at DraftKings Sportsbook
  • Over/Under: 43

Are you on board with Colt McCoy if he is starting, or was last year a one-time deal against the 49ers?

Go Cardinals!