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Cardinals-49ers Week 15 preview, matchups to watch, and picks

Jess and Seth preview the Arizona Cardinals matchup with the San Francisco 49ers.

NFL: Arizona Cardinals at San Francisco 49ers Cary Edmondson-USA TODAY Sports

Happy game day one and all.

The Arizona Cardinals take on the San Francisco 49ers today and Jess and I are back to take a look at some of the better prop bets and picks to make during the game.

We start out by taking a look at the Niners this season and wonder, can anyone stop them?

From there we look at the key matchups in the game, see if there is anywhere the Arizona Cardinals can take advantage, and from there we give you some of the best bets to make heading into this one.

Enjoy the show with the embedded player above or by subscribing to the show on Apple Podcasts, Spotify or your favorite podcast platform, so you never miss a show. Make sure as well to give it a five-star rating!

Times and topics:

(1:00) Breaking down the Niners and their season

(24:02) Cardinals-49ers keys and matchups

(36:55) Picks, predictions and prop bets